Vitamin K2 (MK-7) Oil 1%: Essential Nutrient for Bone and Cardiovascular Health
Technical Overview
Vitamin K2 (MK-7) is a specialized formulation containing menaquinone-7, the most bioavailable and long-acting homologue in the vitamin K2 family. This oil-based preparation features a standardized 1% concentration, providing precise dosing capabilities for nutritional applications. MK-7 exhibits superior pharmacokinetic properties compared to other K vitamins, with a serum half-life of approximately 72 hours, enabling sustained biological activity. The molecular structure of MK-7 (2-methyl-1,4-naphthoquinone with a 7-isoprenyl unit side chain) confers optimal lipophilicity and enhanced tissue distribution.
Applications & Advantages
Vitamin K2 (MK-7) serves as a critical ingredient in nutraceuticals, dietary supplements, and functional foods targeting bone and cardiovascular health. Its primary mechanism involves activating osteocalcin and matrix Gla proteins, thereby directing calcium to bone tissue while inhibiting arterial calcification. This dual action provides significant advantages over calcium supplementation alone. The oil-based 1% formulation ensures stability, homogeneous distribution in various matrices, and protection against oxidative degradation. Its applications extend to geriatric nutrition, women's health products, and sports nutrition formulations.
Commercial Development
Commercial interest in MK-7 emerged following pioneering research on Japanese natto consumption and cardiovascular outcomes in the early 2000s. The first standardized MK-7 ingredient, MenaQ7®, was commercialized by NattoPharma (now part of Gnosis by Lesaffre). Other significant manufacturers include Kappa Bioscience with their K2VITAL® and Viridis BioPharma with vitaMK7®. The development of stabilized oil formulations at 1% concentration represented a significant advancement in delivery technology, enabling consistent potency and extended shelf-life.
Current Offering
Shenzhen Bohr Chemical Co., Ltd currently distributes premium-grade Vitamin K2 (MK-7) Oil 1% sourced from reliable manufacturers adhering to stringent quality protocols. Our product meets international regulatory standards including USP, EP, and JP specifications, making it suitable for global comsumption. We serve both domestic Chinese markets and international clients in the nutraceutical, pharmaceutical, and functional food sectors. Our technical team provides comprehensive support for formulation development and stability optimization, ensuring successful incorporation of this valuable nutrient into diverse applications.